Sergio Sosa-Estani Selected Research

benzonidazole (benznidazole)

1/2021	Benznidazole in Chagas disease study: do the data justify progression to phase 3? - Authors' reply.
1/2021	New regimens of benznidazole monotherapy and in combination with fosravuconazole for treatment of Chagas disease (BENDITA): a phase 2, double-blind, randomised trial.
1/2020	Fixed vs adjusted-dose benznidazole for adults with chronic Chagas disease without cardiomyopathy: A systematic review and meta-analysis.
1/2020	New Scheme of Intermittent Benznidazole Administration in Patients Chronically Infected with Trypanosoma cruzi: Clinical, Parasitological, and Serological Assessment after Three Years of Follow-Up.
1/2019	Strategies to enhance access to diagnosis and treatment for Chagas disease patients in Latin America.
1/2019	Effects of Trypanocidal Treatment on Echocardiographic Parameters in Chagas Cardiomyopathy and Prognostic Value of Wall Motion Score Index: A BENEFIT Trial Echocardiographic Substudy.
10/2018	Clinical and pharmacological profile of benznidazole for treatment of Chagas disease.
2/2017	Benznidazole and Posaconazole in Eliminating Parasites in Asymptomatic T. Cruzi Carriers: The STOP-CHAGAS Trial.
2/2016	New Scheme of Intermittent Benznidazole Administration in Patients Chronically Infected with Trypanosoma cruzi: a Pilot Short-Term Follow-Up Study with Adult Patients.
1/2016	Electrocardiographic Abnormalities and Treatment with Benznidazole among Children with Chronic Infection by Trypanosoma cruzi: A Retrospective Cohort Study.

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Sergio Sosa-Estani Research Topics

Disease

21	Chagas Disease (American Trypanosomiasis) 01/2022 - 01/2004
12	Infections 01/2019 - 08/2004
5	Chagas Cardiomyopathy 01/2019 - 12/2006
3	Heart Failure 10/2015 - 07/2008
3	Trypanosomiasis 01/2013 - 07/2008
3	Sexually Transmitted Diseases (Sexually Transmitted Disease) 01/2011 - 08/2004
2	Parasitemia 11/2021 - 01/2013
2	Exanthema (Rash) 01/2021 - 01/2020
2	Cardiomyopathies (Cardiomyopathy) 01/2020 - 07/2009
2	Persistent Infection 01/2016 - 01/2015
2	Ventricular Tachycardia 10/2015 - 07/2008
2	Stroke (Strokes) 10/2015 - 07/2008
2	Heart Arrest (Cardiac Arrest) 10/2015 - 07/2008
2	HIV Infections (HIV Infection) 01/2011 - 08/2006
2	Heart Diseases (Heart Disease) 07/2009 - 07/2008
1	Leukopenia 01/2021
1	Acute Cholecystitis 01/2021
1	Polyps 01/2021
1	Fever (Fevers) 01/2021
1	Neutropenia 01/2021
1	Breast Neoplasms (Breast Cancer) 01/2021
1	Body Weight (Weight, Body) 01/2020
1	Peripheral Nervous System Diseases (PNS Diseases) 01/2020
1	Asymptomatic Diseases 01/2020
1	Drug-Related Side Effects and Adverse Reactions 01/2019
1	Clinical Deterioration 10/2015
1	Disease Progression 07/2009
1	Syphilis 05/2008
1	Parasitic Diseases (Parasitic Disease) 12/2006
1	Tuberculosis (Tuberculoses) 08/2006
1	HIV Seropositivity 04/2005

Drug/Important Bio-Agent (IBA)

17	benzonidazole (benznidazole)IBA 01/2021 - 01/2004
4	Pharmaceutical PreparationsIBA 01/2022 - 08/2004
3	AntigensIBA 11/2021 - 01/2008
3	NifurtimoxIBA 01/2021 - 01/2015
3	Biomarkers (Surrogate Marker)IBA 09/2015 - 07/2009
3	AntibodiesIBA 04/2011 - 01/2008
3	Cocaine (Cocaine HCl)IBA 01/2011 - 08/2006
2	Antiparasitic Agents (Antiparasitics)IBA 01/2021 - 01/2021
2	DNA (Deoxyribonucleic Acid)IBA 09/2015 - 01/2013
1	Aspartate Aminotransferases (Aspartate Transaminase)IBA 01/2021
1	Alanine Transaminase (SGPT)IBA 01/2021
1	gamma-Glutamyltransferase (gamma-Glutamyl Transpeptidase)IBA 01/2021
1	ElementsIBA 01/2020
1	SuspensionsIBA 01/2020
1	posaconazole FDA Link 02/2017
1	Silica GelIBA 01/2013
1	SYBR Green IIBA 01/2013
1	A-factor (Streptomyces)IBA 01/2013
1	Hepatitis B Surface Antigens (HBsAg)FDA Link 01/2011
1	Surface Antigens (Surface Antigen)IBA 01/2011
1	ImmunosorbentsIBA 01/2010
1	EnzymesIBA 01/2010
1	Thioctic Acid (Lipoic Acid)IBA 01/2004

Therapy/Procedure

7	Therapeutics 10/2015 - 12/2006
2	Heart Transplantation (Grafting, Heart) 10/2015 - 07/2008
2	Secondary Prevention 01/2012 - 07/2009
1	Duration of Therapy 01/2021
1	Implantable Defibrillators (Implantable Cardioverter-Defibrillator) 10/2015
1	Aftercare (After-Treatment) 01/2015
1	Drug Therapy (Chemotherapy) 01/2013
1	Defibrillators (Defibrillator) 07/2008
1	Condoms (Condom) 04/2005